Drug eruption - Oogun Eruption
☆ Ninu awọn abajade 2022 Stiftung Warentest lati Jẹmánì, itẹlọrun alabara pẹlu ModelDerm jẹ kekere diẹ ju pẹlu awọn ijumọsọrọ telemedicine isanwo.
Oogun Eruption (Drug eruption) jẹ ifihan nipasẹ ipa lori gbogbo ara.
References
Awọn aati awọ-ara ti o ṣẹlẹ nipasẹ oogun, ti a mọ si eruptions oogun, le ma le ni igba miiran. Awọn aati lile wọnyi, ti a pe ni severe cutaneous adverse drug reactions (SCARs) , ni a ka si eewu-aye. Wọn pẹlu awọn ipo bii Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) . Lakoko ti SCARs jẹ toje, ni ayika 2% ti awọn alaisan ile-iwosan ni iriri wọn.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Arabinrin ẹni ọdun mọkanlelọgbọn kan ṣabẹwo si ẹka ile-ẹkọ nipa iwọ-ara pẹlu patch pupa ti ko ni irora lori oke ẹsẹ ọtún rẹ. O mu iwọn lilo kan ti doxycycline (100 miligiramu) ni ọjọ ṣaaju, ni atẹle itọju laser picosecond fun awọn aleebu irorẹ. Ni ọdun to kọja, o ni iriri iru ọran kan ni aaye kanna lẹhin ti o mu iwọn kanna ti doxycycline itọju lesa lẹhin-lesa. Ko ni itan-akọọlẹ iṣoogun pataki ati pe ko si awọn ami aisan miiran, bii iba, ni agbegbe tabi jakejado ara rẹ.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) ati toxic epidermal necrolysis (TEN) jẹ awọn ọna meji ti iṣesi awọ ara to ṣe pataki, ti o yatọ si awọn ipo awọ miiran bii erythema multiforme major ati iṣọn awọ ara staphylococcal scalded, ati awọn aati oogun. SJS/TEN jẹ iṣesi ti o ṣọwọn ati lile ti o nfa awọ ara kaakiri ati ibajẹ awo awọ mucous, nigbagbogbo pẹlu awọn ami aisan eto. Ni diẹ sii ju 80% ti awọn ọran, oogun jẹ idi.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Oògùn eruptions ti wa ni ayẹwo nipataki lati awọn egbogi itan ati isẹgun ayewo. Biopsy awọ ara, awọn idanwo ẹjẹ tabi awọn idanwo ajẹsara le tun wulo.
Awọn apẹẹrẹ ti awọn oogun ti o wọpọ ti o fa eruption jẹ awọn oogun apakokoro ati awọn oogun apakokoro miiran, awọn oogun sulfa, awọn oogun egboogi-iredodo ti kii ṣe sitẹriọdu (NSAIDs), awọn aṣoju kimoterapi fun awọn aarun buburu, awọn anticonvulsants ati awọn oogun psychotropic.
○ Ayẹwo ati Itọju
Ti o ba ni iba (iwọn otutu ara ti o pọ si), o yẹ ki o wa itọju ilera ni kete bi o ti ṣee. Oogun ti a fura si yẹ ki o dawọ duro (fun apẹẹrẹ awọn oogun apakokoro, awọn oogun egboogi-iredodo ti kii-sitẹriọdu). Ṣaaju lilo si ile-iwosan, awọn antihistamines ti ẹnu bi cetirizine tabi loratadine le ṣe iranlọwọ fun nyún ati sisu.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Idanwo ẹjẹ (CBC, LFT, iye eosinophil)
Awọn sitẹriọdu ẹnu ati awọn antihistamines pẹlu iwe-aṣẹ dokita